NSAIDs are a collective class of compounds widely used in several different indications. The drugs under this class have effects ranging from analgesic, antipyretic, anti-inflammatory, cardio-protection, with varying effectiveness levels. These are some of the most commonly available OTC (over the counter) drugs. The most common of them include paracetamol, diclofenac, and aspirin. They are sometimes referred to as non-narcotic, non-opioid, or aspirin-like analgesics. This article highlights Analgesic Brands and popular analgesics prescribed to relieve pain.
Popular Analgesic Brands
| Brand Name | Composition | Company | Pack |
|---|---|---|---|
| CALPOL | PARACETAMOL | GSK |  |
| CHYMORAL | CHYMOTRYPSIN + TRYPSIN | TORRENT PHARMA |  |
| COMBIFLAM | IBUPROFEN + PARACETAMOL | SANOFI |  |
| DOLO | PARACETAMOL | MICRO LABS |  |
| DOLONEX | PIROXICAM | PFIZER |  |
| DYNAPAR AQ | DICLOFENAC SODIUM SALT | TROIKAA PHARMA |  |
| ENZOFLAM | DICLOFENAC SODIUM SALT + PARACETAMOL + SERRAPEPTASE | ALKEM |  |
| FLEXON | IBUPROFEN + PARACETAMOL | ARISTO PHARMA |  |
| HCQS | HYDROXYCHLOROQUINE SULFATE | IPCA LABS |  |
| HIFENAC-P | ACECLOFENAC + PARACETAMOL | INTAS PHARMA |  |
| IBUGESIC PLUS | IBUPROFEN + PARACETAMOL | CIPLA |  |
| KETOROL | KETOROLAC TROMETAMINE | DR REDDYS LABS |  |
| LYSER-D | DICLOFENAC SODIUM SALT + SERRAPEPTASE | COMED CHEMICALS |  |
| NISE | NIMESULIDE | DR REDDYS LABS |  |
| P-250 | PARACETAMOL | APEX |  |
| SARIDON | CAFFEINE + PARACETAMOL + PROPYPHENAZONE | PIRAMALHEALTHCARE |  |
| SIGNOFLAM | ACECLOFENAC + PARACETAMOL + SERRAPEPTASE | LUPIN LIMITED |  |
| SUMO | NIMESULIDE + PARACETAMOL | ALKEM |  |
| SUMO-L | PARACETAMOL | ALKEM |  |
| ULTRACET | PARACETAMOL + TRAMADOL HYDROCHLORIDE | JANSSEN |  |
| VOLINI | DICLOFENAC DIETHYLAMINE + LINUM USITATISSIMUM OIL + MENTHOL + SALICYLIC ACID METHYL ESTER | SUN |  |
| VOVERAN | DICLOFENAC SODIUM SALT | NOVARTIS INTL. |  |
| ZERODOL-P | ACECLOFENAC + PARACETAMOL | IPCA LABS |  |
| ZERODOL-SP | ACECLOFENAC + PARACETAMOL + SERRAPEPTASE | IPCA LABS |  |
| ZERODOL-TH | ACECLOFENAC + THIOCOLCHICOSIDE | IPCA LABS |  |
How do NSAIDs relieve pain?
Analgesic Brands (NSAIDs) predominantly act on peripheral pain mechanisms and the CNS to raise the pain threshold.
The effect elicited was first noticed by Vane and his coworkers in 1971, that aspirin and some NSAIDs blocked prostaglandin (PG) generation. PG is known to induce hyperalgesia (a high degree of pain). This modulates the transducing property of free nerve endings. Such stimuli that normally do not elicit pain can do so.
References:
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