Analgesic Brands: popular analgesics for Pain Relief

NSAIDs are a collective class of compounds widely used in several different indications. The drugs under this class have effects ranging from analgesic, antipyretic, anti-inflammatory, cardio-protection, with varying effectiveness levels. These are some of the most commonly available OTC (over the counter) drugs. The most common of them include paracetamol, diclofenac, and aspirin. They are sometimes referred to as non-narcotic, non-opioid, or aspirin-like analgesics. This article highlights Analgesic Brands and popular analgesics prescribed to relieve pain.

Popular Analgesic Brands

Brand Name	Composition	Company	Pack
CALPOL	PARACETAMOL	GSK
CHYMORAL	CHYMOTRYPSIN + TRYPSIN	TORRENT PHARMA
COMBIFLAM	IBUPROFEN + PARACETAMOL	SANOFI
DOLO	PARACETAMOL	MICRO LABS
DOLONEX	PIROXICAM	PFIZER
DYNAPAR AQ	DICLOFENAC SODIUM SALT	TROIKAA PHARMA
ENZOFLAM	DICLOFENAC SODIUM SALT + PARACETAMOL + SERRAPEPTASE	ALKEM
FLEXON	IBUPROFEN + PARACETAMOL	ARISTO PHARMA
HCQS	HYDROXYCHLOROQUINE SULFATE	IPCA LABS
HIFENAC-P	ACECLOFENAC + PARACETAMOL	INTAS PHARMA
IBUGESIC PLUS	IBUPROFEN + PARACETAMOL	CIPLA
KETOROL	KETOROLAC TROMETAMINE	DR REDDYS LABS
LYSER-D	DICLOFENAC SODIUM SALT + SERRAPEPTASE	COMED CHEMICALS
NISE	NIMESULIDE	DR REDDYS LABS
P-250	PARACETAMOL	APEX
SARIDON	CAFFEINE + PARACETAMOL + PROPYPHENAZONE	PIRAMALHEALTHCARE
SIGNOFLAM	ACECLOFENAC + PARACETAMOL + SERRAPEPTASE	LUPIN LIMITED
SUMO	NIMESULIDE + PARACETAMOL	ALKEM
SUMO-L	PARACETAMOL	ALKEM
ULTRACET	PARACETAMOL + TRAMADOL HYDROCHLORIDE	JANSSEN
VOLINI	DICLOFENAC DIETHYLAMINE + LINUM USITATISSIMUM OIL + MENTHOL + SALICYLIC ACID METHYL ESTER	SUN
VOVERAN	DICLOFENAC SODIUM SALT	NOVARTIS INTL.
ZERODOL-P	ACECLOFENAC + PARACETAMOL	IPCA LABS
ZERODOL-SP	ACECLOFENAC + PARACETAMOL + SERRAPEPTASE	IPCA LABS
ZERODOL-TH	ACECLOFENAC + THIOCOLCHICOSIDE	IPCA LABS

How do NSAIDs relieve pain?

Analgesic Brands (NSAIDs) predominantly act on peripheral pain mechanisms and the CNS to raise the pain threshold. 

The effect elicited was first noticed by Vane and his coworkers in 1971, that aspirin and some NSAIDs blocked prostaglandin (PG) generation. PG is known to induce hyperalgesia (a high degree of pain). This modulates the transducing property of free nerve endings. Such stimuli that normally do not elicit pain can do so.

References:

1. NSAIDs: Pain Relief, Classification, Uses
2. Diclofenac- NSAID and its pharmacology
3. Paracetamol- Popular brands and Pharmacology
4. Acetylsalicylic Acid or Aspirin – for Pain relief