Category of Drug Imipenem + Cilastatin is an Anti-Infective drug Mechanism of Action Indications Imipenem + Cilastatin is used forSevere aerobic and anaerobic Gram-positive and Gram-negative infections in hospital-acquired infections Well KnownPharmaceutical Brands Available dosage forms INJECTION Dose Contraindications 1. Hypersensitivity to beta-lactam antibiotics2. Local anaesthetics of the amide-type and inpatients with severe […]
Category of Drug Procarbazine is Immunosuppressives Drug Mechanism of Action Indications Procarbazine is used for1. Part of MOPP regimen in Hodgkin’s and Non-Hodgkin’s lymphomas. Well KnownPharmaceutical Brands Available dosage forms TABLETS Dose Contraindications 1. Hypersensitivity2. Pregnancy 3. Lactation Precautions 1. Ulceration2. Haemorrhage3. Leucopenia4. Renal Impairment5. Hepatic Impairment Adverse Effects 1. leucopenia2. Anaemia3. Thrombocytopenia4. Hypotension5.
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Category of Drug Cloxacillin is an Anti-Infective drug Mechanism of Action Indications Cloxacillin is used for 1. Mulbacillary (MB) leprosy2. Type 2 lepra reactions3. Gram-positive infection includingresistant staphylococci. Well KnownPharmaceutical Brands Available dosage forms 1. CAPSULES2. INJECTION3. DRY SYRUP Dose Contraindications Hypersensitivity to penicillins Precautions 1. History of allergy2. Renal and hepatic impairment3.
Category of Drug Paclitaxel is Immunosuppressives Drug Mechanism of Action Indications Paclitaxel is used forMetastatic ovarian and breast cancer Well KnownPharmaceutical Brands Available dosage forms INJECTION Dose Contraindications 1. Hypersensivity2. Severe hepatic impairment3. lactation4. Pregnancy Precautions Adverse Effects 1. Myelosuppression2. Peripheral neuropathy3. Alopecia4. Muscle pain5. Nausea6. Vomiting7. Hypersensitivity reactions8. Myalgia9. Arthralgia Pregnancy
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Category of Drug Mitomycin is Immunosuppressives Drug Mechanism of Action Indications Mitomycin is used for1. Adenocarcinoma2. Lymphosarcoma andseminoma3. Superficial bladder cancer Well KnownPharmaceutical Brands Available dosage forms INJECTIONS Dose Contraindications 1. Pregnancy2. Bone marrow depression3. Severe anaemia4. Thrombocytopenia5. lactation Precautions It causes delayed bone-marrow toxicity and therefore it is usually administered at 6-weeklyintervals
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Category of Drug Methotrexate is Immunosuppressives Drug Mechanism of Action Indications Methotrexate is used for1. Carcinoma of the breast2. Head and neck and lung3. Trophoblastic tumours4. Acute lymphoblastic leukaemia5. Meningeal leukaemia6. Non-Hodgkin’s lymphomas7. Advanced cases of mycosis fungoides8. Non-metastatic osteosarcoma9. Severe rheumatoid arthritis Well KnownPharmaceutical Brands Available dosage forms 1. TABLETS2. INJECTION3. VIALS4. GEL
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Category of Drug 6-Mercaptopurine is Immunosuppressives Drug Mechanism of Action Indications 6-Mercaptopurine is used for1. Acute leukaemias2. Chronic granulocytic leukaemia3. Choriocarcinoma Well KnownPharmaceutical Brands Available dosage forms 1. INJECTION 2. TABLET Dose Contraindications 1. Hypersensitivity2. Pregnancy3. Lactation Precautions 1. Monitor blood count2. Uric acid levels3. Renal impairment 4. Hepatic impairment5. Interactions Adverse Effects
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Category of Drug Melphalan is Immunosuppressives Drug Mechanism of Action Indications Melphalan is used 1. Breast carcinoma2. Multiple myeloma3. Advanced ovarian carcinoma4. Malignant melanoma 5. Polycythaemia vera. Well KnownPharmaceutical Brands Available dosage forms 1. TABLETS 2. INJECTION Dose Contraindications 1. Pregnancy2. Hypersensitivity3. Myelosuppression4. lactation Precautions 1. Hepatic impairment 2. Renal impairment 3. Interactions
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Category of Drug L- Asparaginase is Immunosuppressives Drug Mechanism of Action Indications L- Asparaginase is used for1. Acute lymphoblastic leukaemia Well KnownPharmaceutical Brands Available dosage forms INJECTION Dose Contraindications 1. Pregnancy 2. Lactation Precautions Adverse Effects Pregnancy Category
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Category of Drug Lamotrigine is a Anticonvulsants/Antiepileptics drug Mechanism of Action Indications Lamotrigine is used for 1. Partial seizures 2. Secondary generalised tonic-clonic seizures. Well KnownPharmaceutical Brands Available dosage forms TABLETS Dose Contraindications 1. Child less than 12 years 2. Hypersensitivity 3. Severe hepatic and renal impairment. Precautions 1. Monitoring of liver
