Doxycycline

Doxycycline Drug- Uses, Side Effects, Popular Brands

Category of DrugDoxycycline is an Anti-Infective drug
Read More: Which are the popular antibiotics prescribed for infections?
Mechanism of ActionTetracyclines such as doxycycline are thought to inhibit translation by binding to the 16S rRNA portion of the ribosome 1, preventing binding of tRNA to the RNA-30S bacterial ribosomal subunit, which is necessary for the delivery of amino acids for protein synthesis.

As a result of the above actions, the initiation of protein synthesis by polyribosome formation is blocked. This stops the replication of bacteria and produces a bacteriostatic effect.
Indications Doxycycline drug is used for
1. Respiratory-tract infections
2. urinary-tract infections
3. syphilis
4. lymphogranuloma venereum
5. pelvic inflammatory disease
6. Lyme disease
7. prophylaxis of malaria for pregnant women and non-immune individuals at risk
Well Known
Pharmaceutical Brands
DOXICIP- CIPLA
DOXIFIC- GUFIC
DOXT-S- DRL
DOXYFAV- AUREATE HEALTHCARE
DOXYTOP- OVERSEAS
DOXYTRAC- INVISION
DOXYWELL- NOEL PHARMA
Available dosage forms1. TABLETS/CAPSULES
2. SYRUP
ᐅ Buy Doxycycline 100mg Tablets Online | HealthExpress UK
DoseInitial dose: 200 mg orally on the first day, given in 2 divided doses (100 mg every 12 hours)

Maintenance dose: 100 mg orally once a day OR 50 mg orally every 12 hours
Contraindications 1. Pregnancy
2. Children
3. Porphyria
4.Systemic lupus erythematosus
5. Hypersensitivity to tetracycline.
Precautions 1. Avoid exposure to sunlight or sunlamps-
photosensitivity reported
2. Renal impairment
3. Hepatic impairment
4. Lactation
5. Interactions
Adverse Effects1. Gastrointestinal disturbances
2. anorexia, erythema
3. Photosensitivity
4. Hypersensitivity reactions
5. Headache and visual disturbances
6. Hepatotoxicity
7. blood disorders
8. pancreas and antibiotic-associated colitis reported
9. Staining of growing teeth and occasional
dental hypoplasia
Pregnancy Category D

Refrernces

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