| Category of Drug | Warfarin is a Drug Affecting Coagulation |
| Mechanism of Action | |
| Indications | Warfarin is used for 1. Prophylaxis of embolisation in rheumatic heart disease and atrial fibrillation 2. Prophylaxis after insertion of prosthetic heart valve 3. Prophylaxis and treatment of venous thrombosis and pulmonary embolism 4. Ischaemic attacks 5. Myocardial infarction 6. Valvular heart disease |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | TABLETS |
| Dose | |
| Contraindications | 1. Pregnancy 2. Peptic ulcer 3. Severe hypertension 4. Bacterial endocarditis 5. Hypersensitivity 6. Blood dyscrasias 7. Recent surgery 8. Psychosis 9. Pericardial effusion 10. Cerebrovascular disorder 11. Alcoholism 12. Senility 13. Aneurysm |
| Precautions | 1. Heparin-induced thrombocytopenia 2. Surgery or trauma 3. Vit C, K 4. lactation 5. Alcoholics 6. Purple toes syndrome 7. Discontinue if necrosis develops 8. Elderly 9. Hepatic impairment 10. Renal failure 11. Interactions 12. Lactation |
| Adverse Effects | 1. Haemorrhage 2. Hypersensitivity 3. rash 4. Alopecia 5. Diarrhoea 6. An unexplained drop in haematocrit 7. skin necrosis 8. Jaundice 9. Hepatic dysfunction 10. Nausea 11. Voming and pancreatitis |
| Pregnancy Category | X |
