Furosemide- Indications, Dosage, Contraindications, ADRs

Category of DrugFurosemide is a Drug Used in Heart Failure
Mechanism of Action 
Indications Furosemide is used for
1. Oedema
2. Mild to moderate hypertension
Well Known
Pharmaceutical Brands
Available dosage forms 1. TABLETS
Contraindications 1. Renal failure with anuria
2. Precomatose states associated with liver cirrhosis
3. Severe sodium and water depletion
4. Hypersensitivity to sulphonamides and furosemide
5. Hypokalaemia
6. Addison’s disease
7. lactation
Precautions 1. Monitor electrolytes particularly potassium and Sodium
2. Hypotension
3. Elderly
4. lactation
5. Correct hypovolaemia before using in oliguria
6. Renal impairment
7. Hepatic Impairment
8. Prostac enlargement
9. Porphyria
10. Interactions
11. Gout
12. Impaired micturition
13. The infusion rate should not exceed 4 mg/min to reduce the
risk of ototoxicity
Adverse Effects 1. Hypokalaemia
2. Hypomagnesaemia
3. Hyponatraemia
4. Hypochloraemic alkalosis
5. Increased calcium excretion
6. Hypovolaemia
7. Hyperglycaemia
8. Temporary increase in plasma cholesterol and triglyceride concentration
9. Less commonly hyperuricaemia and gout
10. photosensitivity
Pregnancy Category C

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