Protamine- Indications, Dosage, Contraindications, ADRs

Category of Drug Protamine is a Drug Affecting Coagulation
Mechanism of Action 
Indications Protamine is used for
1. An antidote to overdosage with heparin
2. An antidote for heparin in controlled bleeding
Well Known
Pharmaceutical Brands
Available dosage forms 1. SOLUTION
Precautions  1. If used in excess protamine has an anticoagulant effect
2. Allergic reactions
increased in persons at risk including previous treatment with protamine or protamine insulin
3. Fish allergies
4. Men who are infertile or who have had a vasectomy
5. Pregnancy
6. Lactation
7. Children
Adverse Effects 1. Nausea
2. Voming
3. Lassitude
4. Flushing
5. Hypotension
6. Bradycardia
7. Dyspnoea
8. Allergic reactions
Pregnancy Category C

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