| Category of Drug | Protamine is a Drug Affecting Coagulation |
| Mechanism of Action | |
| Indications | Protamine is used for 1. An antidote to overdosage with heparin 2. An antidote for heparin in controlled bleeding |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | 1. SOLUTION 2. INJECTION |
| Dose | |
| Contraindications | |
| Precautions | 1. If used in excess protamine has an anticoagulant effect 2. Allergic reactions increased in persons at risk including previous treatment with protamine or protamine insulin 3. Fish allergies 4. Men who are infertile or who have had a vasectomy 5. Pregnancy 6. Lactation 7. Children |
| Adverse Effects | 1. Nausea 2. Voming 3. Lassitude 4. Flushing 5. Hypotension 6. Bradycardia 7. Dyspnoea 8. Allergic reactions |
| Pregnancy Category | C |
