Tranexamic Acid

Tranexamic Acid- Indications, Dosage, Contraindications, ADRs

Category of DrugTranexamic Acid is Blood Products and Plasma Substitutes
Mechanism of Action 
Indications Tranexamic Acid is used for
1. Prevention of haemorrhage due to dental procedures in hemophilics
2. Cyclic heavy menstrual bleeding
3. Hereditary angioedema
4. Cone biopsy
5. Epistaxis
6. Traumatic hyphema
Well Known
Pharmaceutical Brands
 
Available dosage forms1. TABLETS
2. INJECTION
Dose 
Contraindications1. Hypersensitivity
2. Acquired defective colour
vision
3. Subarachnoid haemorrhage
4. Active intravascular clotting
5. Pregnancy
6. Interactions
Precautions 1. Renal impairment
2. Disseminated intravascular coagulation
3. Thromboembolic history
4. Coadministration with hormonal
contraceptives may increase the risk of thrombosis
5. Stroke
6. Ligneous conjunctivitis
7. Retinal venous and arterial
occlusion
8. Patients should be instructed to report visual and ocular symptoms promptly
Adverse Effects1. Nausea
2. Voming
3. Diarrhoea
4. Disturbances in colour vision
5. Thromboembolic events
6. Allergic skin reactions
7. Giddiness and hypotension on rapid intravenous injection
Pregnancy Category C

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