Ketamine- Indications, Dosage, Contraindications, ADRs

Category of Drug Ketamine is a drug for Anaesthesia
Mechanism of Action 
Indications Ketamine is used for
1. Induction and maintenance of anaesthesia
2. Analgesia for painful procedures of short duration especially for patients at the risk of hypotension and bronchospasm
Well Known
Pharmaceutical Brands
Available dosage forms INJECTIONS
Contraindications 1. Thyrotoxicosis
2. Hypertension
3. History of cerebrovascular
4. Cerebral trauma
5. Intracerebral mass or haemorrhage or other cause of raised intracranial pressure
6. Open eye injury and
increased intraocular pressure
7. Psychiatric disorders
8. Particularly hallucinations
9. Hypersensitivity to the drug
Precautions 1. Supplementary analgesia often required in surgical procedures involving visceral pain pathways
2. The patient must remain undisturbed but under observation
3. Lactation
4. Children
5. Alcohol intoxicated patients
6. Increased CSF pressure
7. Cardiac decompensation
8. Pregnancy
Adverse Effects1. Hallucinations and other emergence reacons during recovery possibly accompanied by irrational behaviour
2. Transient elevation of pulse rate
and blood pressure common
3. Arrhythmias have occurred
4. Hypotension and bradycardia
occasionally reported
5. Confusion
6. Delirium
7. Mobilliform rash
8. Transient erythema
9. Diplopia
Pregnancy Category B

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