Category of Drug | Diltiazem is Antianginal Drugs |
Mechanism of Action | |
Indications | Diltiazem is used for 1. Angina pectoris due to coronary artery spasm 2. Chronic stable angina 3. Cardiac arrhythmia |
Well Known Pharmaceutical Brands | |
Available dosage forms | 1. TABLETS/TABLETS (SR) 2. CAPSULE 3. INJECTION |
Dose | |
Contraindications | 1. Severe bradycardia 2. Left ventricular failure with pulmonary congestion 3. Second- or third-degree AV block 4. Sick sinus syndrome 5. Lactation |
Precautions | 1. Reduce dose in hepatic and renal impairment 2. Heart failure or significantly impaired left ventricular function 3. Bradycardia 4. First degree AV block or prolonged PR interval 5. Interactions 6. Sinoatrial nodal dysfunction 7. Pregnancy |
Adverse Effects | 1. Bradycardia 2. Sino-atrial block 3. AV block 4. Palpitation 5. Dizziness 6. Hypotension 7. Malaise 8. Asthenia 9. Headache 10. Hot flushes 11. Gastrointestinal disturbances 12. Oedema 13. Photosensitivity 14. Hepatitis 15. Gynaecomastia |
Pregnancy Category | C |
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