Diltiazem

Diltiazem- Indications, Dosage, Contraindications, ADRs

Category of DrugDiltiazem is Antianginal Drugs
Mechanism of Action 
Indications Diltiazem is used for
1. Angina pectoris due to coronary artery spasm
2. Chronic stable angina
3. Cardiac arrhythmia
Well Known
Pharmaceutical Brands
 
Available dosage forms 1. TABLETS/TABLETS (SR)
2. CAPSULE
3. INJECTION
Dose 
Contraindications 1. Severe bradycardia
2. Left ventricular failure with pulmonary congestion
3. Second- or third-degree AV block
4. Sick sinus syndrome
5. Lactation
Precautions 1. Reduce dose in hepatic and renal impairment
2. Heart failure or significantly impaired left ventricular function
3. Bradycardia
4. First degree AV block or prolonged PR interval
5. Interactions
6. Sinoatrial nodal dysfunction
7. Pregnancy
Adverse Effects 1. Bradycardia
2. Sino-atrial block
3. AV block
4. Palpitation
5. Dizziness
6. Hypotension
7. Malaise
8. Asthenia
9. Headache
10. Hot flushes
11. Gastrointestinal disturbances
12. Oedema
13. Photosensitivity
14. Hepatitis
15. Gynaecomastia
Pregnancy Category C

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