| Category of Drug | Dextran 40 is Blood Products and Plasma Substitutes |
| Mechanism of Action | |
| Indications | Dextran 40 is used for 1. Plasma volume expansion during hypovolemic shock when blood not available 2. Prophylaxis of thromboembolic disorders to improve local circulation in peripheral vascular occlusion |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | INFUSION |
| Dose | |
| Contraindications | 1. Hypersensitivity 2. Cardiac decompensation 3. Oliguria or anuria 4. Hemostatic defects 5. Thrombocytopenia 6. Blood coagulation disorder 7. Pulmonary oedema 8. Neonates |
| Precautions | 1. Renal and hepatic impairment 2. Pregnancy 3. lactation 4. Diabetes 5. Cardiac patients 6. Elderly 7. Monitor urine output 8. Monitor for signs of circulatory overload 9. Interactions |
| Adverse Effects | 1. Nausea 2. Voming 3. Local injection site reaction 4. Hypersensitivity and anaphylactoid reactions 5. Increased serum SGOT and SGPT concentrations 6. Osmotic nephrosis |
| Pregnancy Category | C |
