Chlorambucil- Indications, Dosage, Contraindications, ADRs

Category of Drug Chlorambucil is Immunosuppressives Drug
Mechanism of Action 
Indications Chlorambucil is used for
1. Chronic lymphocytic leukaemia
2. Some of non-Hodgkin’s lymphomas
3. Hodgkin’s disease
4. Ovarian cancer
5. Waldenstrom (primary)
Well Known
Pharmaceutical Brands
Available dosage forms TABLETS
Contraindications1. Hypersensitivity
2. Porphyria
3. Pregnancy
4. lactation
Precautions1. Renal impairment
2. Hepatic impairment
Adverse Effects 1. Hepatotoxicity
2. Peripheral neuropathy
3. Cystitis
4. Seizures
5. Pulmonary fibrosis
Pregnancy Category D

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