Bupivacaine- Indications, Dosage, Contraindications, ADRs

Category of Drug Bupivacaine is a drug for Anaesthesia
Mechanism of Action 
Indications Bupivacaine is used for
1. Infiltration anaesthesia
2. Peripheral and sympathetic nerve block
3. Spinal anaesthesia
4. Postoperative pain relief
Well Known
Pharmaceutical Brands
Available dosage forms INJECTION
Contraindications1. Adjacent skin infection
2. Inflamed skin
3. Concomitant anticoagulant therapy
4. Severe anaemia or heart disease
5. Spinal or epidural anaesthesia in the dehydrated or hypovolaemic patient
Precautions1. Respiratory impairment
2. Hepatic impairment
3. Epilepsy
4. Porphyria
5. Myasthenia gravis
6. lactation
7. Interactions
Adverse Effects 1. With excessive dosage or following intravascular injection
2. light-headedness
3. Dizziness
4. Blurred vision
5. Restlessness
6. Tremors and occasionally convulsions rapidly followed by drowsiness
7. Unconsciousness and respiratory failure
8. Cardiovascular toxicity
includes hypotension
9. Heart block and cardiac
10. Hypersensitivity and allergic reactions also occur
Pregnancy Category C

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