Betaxolol- Indications, Dosage, Contraindications, ADRs

Parameters	Description
Category of Drug³	Betaxolol is an Ophthalmological Preparations drug
Mechanism of Action	Betaxolol is a selective blocker of catecholamine stimulation of beta(1)-adrenergic receptors in the heart and vascular smooth muscle.
Indications	Betaxolol is used for Glaucoma
Chemical Structure ²
IUPAC name	1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Molecular details	Molecular Formula: C₁₈H₂₉NO₃ Molecular Weight: 307.4 g/mol
Well Known Pharmaceutical Brands	IOBET- FDC
Available dosage forms	EYE DROPS
Dose ¹	Instillation into the eye Adult- 1 to 2 drops, twice daily. Child- Not recommended.
Pharmacokinetic properties	1. bioavailability of 89% ± 5% 2. Volume of distribution- Not Available 3. Protein binding- 50% 4. Metabolism- Primarily hepatic. 5. Half-life- 14-22 hours
Contraindications	1. Systemic absorption may follow topical application to the eyes 2. Heart block, or uncontrolled heart failure 3. Hypersensitivity
Precautions	1. Avoid in asthma 2. Poor cardiac reserve 3. Hepatic impairment 4. Not for injection 5. Pregnancy
Adverse Effects	1. Ocular stinging 2. Burning 3. Pain 4. Itching 5. Erythema 6. Dry eyes 7. Allergic reactions
Pregnancy Category	C

Other Ophthalmic preparation