NOVEL DRUG DELIVERY SYSTEMS (BP-704)

NDDS e-learning resource is designed to impart basic knowledge, and understand various approaches in novel drug delivery systems.

Textual Notes:

NDDS Syllabus Chapters (Courtesy: PCI)

  1. Controlled drug delivery systems: Introduction, terminology/definitions, and rationale,
  2. advantages, disadvantages, selection of drug candidates. Approaches to design controlled release formulations based on diffusion, dissolution, and ion exchange principles.
  3. Physicochemical and biological properties of drugs relevant to controlled release formulations
  4. Polymers: Introduction, classification
  5. Polymers: properties, advantages
  6. application of polymers in the formulation of controlled release drug delivery systems.
  7. Microencapsulation: Definition, advantages, and disadvantages
  8. Microencapsulation: microspheres/microcapsules, microparticles
  9. Methods of microencapsulation
  10. Microencapsulation: applications
  11. Mucosal Drug Delivery system: Introduction, Principles of bioadhesion/mucoadhesion
  12. Mucosal Drug Delivery system: concepts, advantages, and disadvantages
  13. Transmucosal permeability and formulation considerations of buccal delivery systems
  14. Implantable Drug Delivery Systems: Introduction, advantages, and disadvantages
  15. Implantable Drug Delivery Systems: the concept of implants and osmotic pump
  16. Transdermal Drug Delivery Systems: Introduction, Permeation through skin, factors
  17. affecting permeation, permeation enhancers, basic components of TDDS, formulation
  18. approaches
  19. Gastro retentive drug delivery systems: Introduction, advantages, disadvantages,
  20. approaches for GRDDS – Floating, high-density systems, inflatable and gastroadhesive systems and their applications
  21. Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays, nebulizers
  22. Targeted drug Delivery: Concepts and approaches advantages and disadvantages,
  23. introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies, and their applications
  24. Ocular Drug Delivery Systems: Introduction, intraocular barriers, and methods to overcome –Preliminary study, ocular formulations, and ocuserts
  25. Intrauterine Drug Delivery Systems: Introduction, advantages, and disadvantages.
  26. Intrauterine Drug Delivery Systems: development of intrauterine devices (IUDs)
  27. Intrauterine Drug Delivery Systems: applications
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