| Category of Drug | Vancomycin is an Anti-Infective drug |
| Mechanism of Action | Vancomycin provides bactericidal action. Its inhibits cell-wall biosynthesis. |
| Indications | Vancomycin is used for 1. Methicillin-resistant staphylococcal pneumonia 2. Staphylococcal meningitis 3. Endocarditis prophylaxis |
| Well Known Pharmaceutical Brands | VANLID- CIPLA VANTOX-CP- SAMARTH PHARMA VANKING-NEON LABS VANCOGRAM- ZYDUS CADILA  |
| Available dosage forms | 1. TABLETS 2. INJECTION 3. CAPSULE |
| Dose | Regular dose: 1 to 1.5g BID Adults: 500 mg BID or 1g once daily. Children- 15 mg/kg body weight TID (max. 2g daily). |
| Contraindications | Allergy to corn/corn products, hypersensitivity. |
| Precautions | 1. Avoid rapid infusion 2. Rotate infusion sites 3. Renal impairment 4. Elderly 5. History of deafness-avoid 6. The plasma-vancomycin concentration measured after 3 or 4 doses |
| Adverse Effects | 1. Nephrotoxicity including renal failure and interstitial nephritis 2. Ototoxicity 3. Blood disorders 4. Nausea 5. Chills 6. Fever 7. Eosinophilia 8. Anaphylaxis 9. Rashes 10. Toxic epidermal necrolysis and vasculitis |
| Pregnancy Category | C |
