Trifluoperazine- Indications, Dosage, Contraindications, ADRs

Category of Drug Trifluoperazine is Antipsychotics drug
Mechanism of Action 
Indications Trifluoperazine is used for
1. Schizophrenia
2. Non-psychotic anxiety
3. Acute psychosis
Well Known
Pharmaceutical Brands
Available dosage forms1. TABLETS
Contraindications1. Hypersensitivity to phenothiazines
2. Bone marrow depression
3. Blood dyscrasias
4. Pre-existing CNS depression and coma
5. Pheochromocytoma
Precautions1. Myasthenia gravis
2. Renal and hepatic impairment
3. Benign prostatic hyperplasia
4. Glaucoma
5. Epilepsy
6. Exposure to extreme heat or phosphorous insecticides
7. Interactions
8. Pregnancy
Adverse Effects1. Extra pyramidal symptoms particularly in children
2. Elderly and debilitated patients
more frequently at doses exceeding 6 mg daily
3. Pancytopenia
4. Thrombocytopenia
5. Hyperpyrexia
6. Dizziness
7. Anorexia
8. Insomnia
9. Dry mouth
10. Blurred vision
11. Postural hypotension
Pregnancy Category C

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