| Category of Drug | Cotrimoxazole is an Anti-Infective drug |
| Mechanism of Action | |
| Indications | Cotrimoxazole is used for 1. Urinary-tract infections 2. Respiratory-tract infections |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | 1. TABLETS 2. SUSPENSION |
| Dose | |
| Contraindications | 1. Hypersensitivity to sulfonamides or trimethoprim 2. Porphyria 3. Marked liver parenchymal damage 4. Blood dyscrasias, 5. Severe renal insufficiency |
| Precautions | 1. Renal impairment 2. Hepatic impairment 3. Maintain adequate fluid intake 4. Avoid in blood disorders 5. Monitor blood counts and discontinue immediately if blood disorder develops 6. Rash-discontinue immediately 7. Predisposition to folate deficiency 8. Elderly 9. G-6-PD deficiency 10. lactation 11. Pregnancy |
| Adverse Effects | 1.Nausea 2. Vomiting 3. Diarrhoea 4. Headache 5. Hypersensitivity reactions 6. photosensitivity 7. Serum sickness 8. Crystalluria-resulting in haematuria 9. oliguria 10. Anuria 11. Blood disorders including granulocytopenia 12. Aplastic anaemia 13. Purpura-discontinue immediately 14. Hallucinations and electrolyte disturbances |
| Pregnancy Category | C |
