| Category of Drug | Thiopental is a drug for Anaesthesia |
| Mechanism of Action | |
| Indications | Thiopental is used for 1. Induction of anaesthesia prior to administration of inhalational anaesthetic 2. anaesthesia of short duration 3. Preferred if cerebral ischemia is expected |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | STERILE POWDER |
| Dose | |
| Contraindications | 1. Inability to maintain airway 2. Hypersensitivity to barbiturates 3. Cardiovascular disease 4. Dyspnoea or obstructive respiratory disease 5. Porphyria 6. Hypotension or shock 7. Addison’s disease 8. Hepatic or renal dysfunction 9. Increased blood urea |
| Precautions | 1. Local extravasation can result in extensive tissue necrosis and sloughing 2. Intra-arterial injection causes intense pain and may result in artery spasm 3. Hepatic impairment 4. Interactions 5. Patients with advanced cardiac disease 6. Increased intracranial pressure 7. Asthma 8. Myasthenia Gravis 9. Endocrine insufficiency |
| Adverse Effects | 1. Respiratory depression 2. Myocardial depression 3. Cardiac arrhythmias 4. Somnolence 5. Bronchospasm 6. urticaria 7. Vasodilation 8. Apnoea 9. Emergence delirium 10. Headache 11. Nausea 12. Oedema |
| Pregnancy Category | C |
