| Category of Drug | Sodium Nitroprusside is Antihypertensive Drugs |
| Mechanism of Action | |
| Indications | Sodium Nitroprusside is used for 1. Hypertensive crisis 2. Congestive heart failure |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | INJECTION |
| Dose | |
| Contraindications | 1. Compensatory hypertension 2. Severe vitamin B12 deficiency 3. Leber optic atrophy 4. Arterial-venous shunting 5. Patients with acute CHF associated with reduced peripheral vascular resistance |
| Precautions | 1. Impaired pulmonary function 2. Hypothyroidism 3. Renal impairment 4. Ischaemic heart disease 5. Impaired cerebral circulation 6. Hyponatraemia 7. Raised intracranial pressure 8. Elderly 9. Hypothermia 10. Monitor blood pressure 11. Blood-cyanide concentration |
| Adverse Effects | 1. Severe hypotension 2. Effects associated with an over-rapid reduction in blood pressure include headache 3. Dizziness 4. Retching 5. Abdominal pain 6. Perspiration 7. Palpitations 8. Apprehension 9. Retrosternal discomfort 10. Muscle twitching 11. Hypothyroidism 12.Increased anaerobic metabolism |
| Pregnancy Category | C |
