Pilocarpine- Indications, Dosage, Contraindications, ADRs

Category of Drug Pilocarpine is Ophthalmological Preparations drug
Mechanism of Action 
Indications Pilocarpine is used for
1. Chronic open-angle glaucoma
2. Ocular hypertension
3. Emergency treatment of acute
angle-closure glaucoma
4. To antagonize the effects of mydriasis and cycloplegia following surgery or ophthalmoscopic examination
5. Accommodative esotropia
Well Known
Pharmaceutical Brands
Available dosage forms EYE DROPS
Contraindications 1. Acute iris
2. Acute uveitis
3. Anterior uveitis
4. Some forms of secondary glaucoma
5. Acute inflammation of anterior segment
6. not advisable after angle closure surgery
Precautions 1. Retinal disease
2. Conjunctival or corneal
3. Monitor intraocular pressure
in chronic open-angle glaucoma and in long-term treatment
4. Cardiac disease
5. Hypertension
6. Asthma
7. Peptic ulceration
8. Urinary-tract obstruction
9. Parkinson’s disease
Adverse Effects 1. Eye pain
2. Blurred vision
3. Ciliary spasm
4. Lacrimation
5. Myopia
6. Browache
7. Conjunctival vascular congestion
8. Superficial keratitis
10. Vitreous haemorrhage and increased pupillary block
11. Hypertension
12. Tachycardia
13. Bronchial spasm
14. Pulmonary oedema
Pregnancy Category C

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