| Category of Drug | Phytomenadione is a Drug Affecting Coagulation |
| Mechanism of Action | |
| Indications | Phytomenadione is used for 1. Antagonist to warfarin 2. Prophylaxis against the haemorrhagic disease of the newborn 3. Vit K deficiency 4. Hematuria 5. Menorrhagia |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | 1. TABLETS 2. INJECTION |
| Dose | |
| Contraindications | Hypersensitivity |
| Precautions | 1. Reduce dose in elderly 2. Hepatic impairment 3. Not an antidote to heparin 5. Can cause haemolysis in patients with G-6-PD 6. Increased risk of severe haemolytic anaemia in neonates after large doses 7. Premature neonates weighing < 2.5 kg 8. Pregnancy |
| Adverse Effects | 1. Hypersensitivity reactions 2. Hypotension and respiratory or a circulatory collapse which may be due to polyethoxylated castor oil surfactant in some injection formulations rather than due to phytomenadione |
| Pregnancy Category | C |
