Nifedipine

Nifedipine- Indications, Dosage, Contraindications, ADRs

Category of Drug Nifedipine is Antihypertensive Drugs
Mechanism of Action 
Indications Nifedipine is used for
1. Hypertension
2. Angina prophylaxis
3. Heart failure
4. Raynaud’s phenomenon
Well Known
Pharmaceutical Brands
 
Available dosage forms 1. TABLETS
2. CAPSULES
Dose 
Contraindications 1. Cardiogenic shock
2. Advanced aortic stenosis,
3. within 1 month of myocardial infarction
4. Unstable or acute attacks of angina
5. Porphyria
6. Hypersensitivity
Precautions 1. Stop if ischaemic pain occurs or existing pain worsens shortly after starting treatment
2. Poor cardiac reserve
3. Heart failure or significantly impaired le ventricular function
4. Monitor drug response in cirrhosis patients
5. Blood pressure monitoring
6. Calcium channel blockers
7. Reduce dose in hepatic impairment
8. pregnancy
9. Lactation
10. Interactions
Adverse Effects 1. Headache
2. Flushing
3. Dizziness
4. Lethargy
5. Tachycardia
6. Palpitations
7. Gravitational oedema
8. Dizziness
9. Nausea
10. Telangiectasis
11. Cholestasis
12. Jaundice
13. Exacerbated angina
14. Cardiovascular
15. Collapse
Pregnancy Category C

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