Methylene Blue (Methylthioninium Chloride)-Antidote

Methylene Blue (Methylthioninium Chloride)-Antidote- Indications, Dosage, Contraindications, ADRs

Category of Drug Methylene Blue (Methylthioninium Chloride)-Antidote is Antidotes and Substances Used in Poisoning
Mechanism of Action 
Indications Methylene Blue (Methylthioninium Chloride)-Antidote is used for
Acute methaemoglobinaemia
Well Known
Pharmaceutical Brands
Available dosage forms INJECTION
Contraindications1. Severe renal impairment
2. Methaemoglobinaemia due to chlorate or induced by
sodium nitrite in treatment of cyanide poisoning
3. Affects ability to drive machinery
Precautions1. G-6-PD deficiency-may cause haemolytic anaemia
2. Monitor blood methaemoglobin
throughout treatment
3. Pregnancy
4. lactation
Adverse Effects1. Nausea
2. Voming
3. Abdominal pain
4. Chest pain
5. Hypertension or hypotension
6. Haemolytic anaemia-in G-6-PD
7. Methaemoglobinaemia-with
high dosage
8. Bluish skin discolouration
9. Blue saliva
10. urine and faeces
Pregnancy Category C

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