Category of Drug | Methylene Blue (Methylthioninium Chloride)-Antidote is Antidotes and Substances Used in Poisoning |
Mechanism of Action | |
Indications | Methylene Blue (Methylthioninium Chloride)-Antidote is used for Acute methaemoglobinaemia |
Well Known Pharmaceutical Brands | |
Available dosage forms | INJECTION |
Dose | |
Contraindications | 1. Severe renal impairment 2. Methaemoglobinaemia due to chlorate or induced by sodium nitrite in treatment of cyanide poisoning 3. Affects ability to drive machinery |
Precautions | 1. G-6-PD deficiency-may cause haemolytic anaemia 2. Monitor blood methaemoglobin throughout treatment 3. Pregnancy 4. lactation |
Adverse Effects | 1. Nausea 2. Voming 3. Abdominal pain 4. Chest pain 5. Hypertension or hypotension reported 6. Haemolytic anaemia-in G-6-PD deficiency 7. Methaemoglobinaemia-with high dosage 8. Bluish skin discolouration 9. Blue saliva 10. urine and faeces |
Pregnancy Category | C |