Glyceryl Trinitrate

Glyceryl Trinitrate- Indications, Dosage, Contraindications, ADRs

Category of DrugGlyceryl Trinitrate is Antianginal Drugs
Mechanism of Action 
Indications Glyceryl Trinitrate is used for
1. Prophylaxis and treatment of angina
2. Myocardial infarction
3. Postoperative hypertension
4. Cardio-pulmonary edema
Well Known
Pharmaceutical Brands
 
Available dosage forms  1. TABLETS
2. CAPSULES
3. INJECTION
4. SUBLINGUAL TAB
5. SPRAY
Dose 
Contraindications 1. Hypersensitivity to nitrates
2. Hypotension
3. Hypovolaemia
4. Raised intracranial pressure
5. Hypertrophic obstructive cardiomyopathy
6. Aortic stenosis
7. Cardiac tamponade
8. Constrictive pericarditis
9. Mitral stenosis
10. Marked anaemia
11. Head trauma
12. Cerebral haemorrhage
13. Angle-closure glaucoma
Precautions 1. Severe hepatic or renal impairment
2. Hypothyroidism
3. Malnutrition
4. Gastrointestinal hypermobility
5. Malabsorption syndrome
6. Hypothermia
7. Recent history of myocardial infarction
8. Interactions
Adverse Effects 1. Throbbing headache
2. Flushing
3. Dizziness
4. Postural hypotension
5. Tachycardia
6. Abdominal pain
7. Collapse
8. Neurological deficit
Pregnancy Category C

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