Flumazenil- Drug Detail Profile

Category of DrugFlumazenil is an Antidotes and Substances Used in Poisoning
Mechanism of Action 
Indications Flumazenil is used for
1. An antidote for benzodiazepine overdose
2. Reversal of sedative effects produced by
benzodiazepines administered during
general anaesthesia or diagnostic or
therapeutic procedures.
Well Known
Pharmaceutical Brands
Available dosage forms INJECTION
Contraindications1. Epilepsy
2. Neuromuscular blockade
3. Hypersensitivity to benzodiazepines
4. Patients of suspected tricyclic antidepressant
5. Raised intracranial pressure
Precautions 1. History of seizures
2. Panic attack
3. Alcohol drug dependence
4. Bleeding disorder
5. Liver disease
6. Head injury
7. Respiratory depression
8. Pregnancy
Adverse Effects 1. Convulsions
2. Fatigue
3. Injection site pains
4. Increased sweating
5. Facial erythema
6. Raised intracranial pressure
7. Agitation
8. Dizziness
9. Abnormal vision
10. May cause complete heart block
Pregnancy Category C

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