Category of Drug | Flumazenil is an Antidotes and Substances Used in Poisoning |
Mechanism of Action | |
Indications | Flumazenil is used for 1. An antidote for benzodiazepine overdose 2. Reversal of sedative effects produced by benzodiazepines administered during general anaesthesia or diagnostic or therapeutic procedures. |
Well Known Pharmaceutical Brands | |
Available dosage forms | INJECTION |
Dose | |
Contraindications | 1. Epilepsy 2. Neuromuscular blockade 3. Hypersensitivity to benzodiazepines 4. Patients of suspected tricyclic antidepressant overdose 5. Raised intracranial pressure |
Precautions | 1. History of seizures 2. Panic attack 3. Alcohol drug dependence 4. Bleeding disorder 5. Liver disease 6. Head injury 7. Respiratory depression 8. Pregnancy |
Adverse Effects | 1. Convulsions 2. Fatigue 3. Injection site pains 4. Increased sweating 5. Facial erythema 6. Raised intracranial pressure 7. Agitation 8. Dizziness 9. Abnormal vision 10. May cause complete heart block |
Pregnancy Category | C |