Flucytosine- Drug Detail Profile

Category of Drug  Flucytosine is an Anti-Infectives
Mechanism of Action 
Indications Flucytosine is used for
1. Adjunct to amphotericin B in cryptococcal meningitis
2. Adjunct to amphotericin B in systemic candidiasis
3. Septicemia
4. Pulmonary infection
Well Known
Pharmaceutical Brands
Available dosage forms1. CAPSULE
Contraindications1. Renal impairment
2. Elderly
3. Blood disorders
4. Pregnancy
5. Hypersensitivity
Precautions1. Elderly
2. Renal impairment
3. Also the use with amphotericin B
4. liver and kidney funcon tests and blood counts required
5. lactation
6. Interactions
7. Pregnancy
Adverse Effects 1. Rash
2. Vomiting
3. Nausea
4. Alterations in liver function tests
5. Less frequently, confusion, hallucinations, convulsions
6. Blood disorders including leukopenia
7. Potentially fatal thrombocytopenia and aplastic anaemia
8. Cardiac arrest
Pregnancy Category C

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