Category of Drug | Ezetimibe is Lipid-Lowering Drug |
Mechanism of Action | |
Indications | Ezetimibe is used for 1. Hypercholesterolemia 2. Hyperlipidaemias 3. Homozygous familial sitosterolaemia |
Well Known Pharmaceutical Brands | |
Available dosage forms | TABLETS |
Dose | |
Contraindications | 1. Hypersensitivity 2. Children below 10 years 3. Pregnancy 4. Interactions 5. lactation 6. Moderate to severe liver disease or unexplained serum transaminase elevation 7. Acute pancreatitis |
Precautions | 1. Renal or mild hepatic impairment 2. Immediately discontinue ezetimibe and any H mg-CoA reductase inhibitor or fibrates if myopathy is diagnosed |
Adverse Effects | 1. Diarrhoea, sinusitis 2. Pharyngitis 3. Cough 4. Arthralgia 5. Myalgia 6. Respiratory infection and fatigue 7. Hepatitis/increased serum transaminases 8. Increased creatinine phosphokinase 9. Myopathy/rhabdomyolysis 10. Headache 11. Nausea 12. Rash 13. Dizziness |
Pregnancy Category | C |