Diazepam

Diazepam-Drug Detail Profile

Category of DrugDiazepam is a  Anconvulsants/Anepilepcs drug
Mechanism of Action 
Indications Diazepam is used for
1. Status epilepsy
2. Emergency management of recurrent seizures
3. Febrile convulsions
4. Seizures associated with poisoning and
medicine withdrawal
5. Adjunct in acute alcohol
withdrawal
6. Premedication
7. Anxiety disorders
Well Known
Pharmaceutical Brands
 
Available dosage forms1. TABLETS
2. CAPSULE
3. SUSPENSION
4. INJECTION
Dose 
Contraindications1. Respiratory depression
2. Acute pulmonary insufficiency
3. Sleep apnoea
4. Severe hepatic impairment
5. Myasthenia gravis
6. avoid injections containing benzyl alcohol in neonates
7. narrow angle glaucoma
8. hypersensitivity to benzodiazepine.
Precautions 1. Respiratory disease
2. muscle weakness
3. History of alcohol or drug abuse
4. Marked personality disorder
5. Pregnancy
6. Lactation
7. Reduce dose in elderly or debilitated patients and in hepatic impairment
8. Renal impairment
9. Avoid prolonged use and abrupt
withdrawal when given intravenously,
Adverse Effects 1. Drowsiness and lightheadedness the next
day
2. Confusion and ataxia
3. Amnesia
4. Dependence
5. muscle weakness
6. occasionally headache
7. vertigo
8. Salivation changes
9. Gastrointestinal disturbances
10. Skin reactions
11. Visual disturbances,
Pregnancy Category D

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