Dexamethasone- Drug Detail Profile

Category of Drug Dexamethasone is Anallergics and Drugs used in Anaphylaxis
Mechanism of Action 
Indications Dexamethasone is used in
1. Adjunct in the emergency treatment
of anaphylaxis
2. Short-term suppression
of inflammation in allergic disorders
3. Adrenocortical insufficiency
4. Ocular inflammation
5. Autoimmune disorders
6. Rheumatic disorder
7. Cerebral oedema
Well Known
Pharmaceutical Brands
Available dosage forms 1. TABLETS
Contraindications1. Untreated systemic infection
2. Administration of live virus vaccines
3. Renal failure
4. Diabetes mellitus
5. Psychosis
6. Osteoporosis
7. Pregnancy
8. CHF
9. Tuberculosis
10. fungal infections of the eye.
Adverse Effects 1. Nausea
2. Dyspepsia
3. Malaise
4. Hiccups
5. Hypersensitivity reactions including anaphylaxis
perineal irritation after intravenous administration
6. Adverse effects associated with long-term corticosteroid treatment
7. Hyperglycaemia
8. Abdominal distension
9. Angioedema
10. Bradycardia
11. Acne
12. Erythema
13. Cushing’s syndrome
14. Oropharyngeal candidiasis
15. Hypothalamic pituitary adrenal axis suppression.
Pregnancy Category C

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