Chloroquine- Drug Detail Profile

Category of DrugChloroquine is an Anti-Infectives
Mechanism of Action 
Indications Chloroquine is used for
1. Treatment of acute malaria caused by P.
malariae and susceptible P. falciparum
2. P.vivax and P. ovale
3. prophylaxis of malaria for pregnant women and non-immune individuals at risk
Well Known
Pharmaceutical Brands
Available dosage forms1. TABLETS
Contraindications 1. Severe haematologic distress or
gastrointestinal distress
2. eye dysfunction
3. Liver disease.
Precautions1. If the patient continues to deteriorate after
chloroquine-suspect resistance and
administer quinine intravenously as
an emergency measure
2. Hepatic impairment
3. Renal impairment
4. Pregnancy
5. lactation
6. May exacerbate psoriasis
7. Neurological disorders
Adverse Effects 1. Headache
2. Gastrointestinal disturbances also convulsions
3. Visual disturbances
4. Depigmentation or loss of hair
5. Rashes
6. Pruritus-may become intolerable
7. Bone-marrow suppression
8. Hypersensitivity reactions such as urticaria and angioedema
Pregnancy Category D

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