Category of Drug | Chloroquine is an Anti-Infectives |
Mechanism of Action | |
Indications | Chloroquine is used for 1. Treatment of acute malaria caused by P. malariae and susceptible P. falciparum 2. P.vivax and P. ovale 3. prophylaxis of malaria for pregnant women and non-immune individuals at risk |
Well Known Pharmaceutical Brands | |
Available dosage forms | 1. TABLETS 2. INJECTION 3. SUSPENSION |
Dose | |
Contraindications | 1. Severe haematologic distress or gastrointestinal distress 2. eye dysfunction 3. Liver disease. |
Precautions | 1. If the patient continues to deteriorate after chloroquine-suspect resistance and administer quinine intravenously as an emergency measure 2. Hepatic impairment 3. Renal impairment 4. Pregnancy 5. lactation 6. May exacerbate psoriasis 7. Neurological disorders |
Adverse Effects | 1. Headache 2. Gastrointestinal disturbances also convulsions 3. Visual disturbances 4. Depigmentation or loss of hair 5. Rashes 6. Pruritus-may become intolerable 7. Bone-marrow suppression 8. Hypersensitivity reactions such as urticaria and angioedema |
Pregnancy Category | D |