Chloramphenicol–Ophthalmological- Indications, Dosage, Contraindications, ADRs

Category of Drug Chloramphenicol-Ophthalmological is Ophthalmological Preparations drug
Mechanism of Action 
IndicationsChloramphenicol-Ophthalmological  is used for
1. Susceptible bacterial infections
2. Corneal ulcers
3. Intraocular infection
4. Keratoconjunctivitis sicca
Well Known
Pharmaceutical Brands
Available dosage forms 1. OINTMENT
Contraindications 1. Pregnancy
2. Lactation
3. Porphyria
4. Hypersensitivity
Precautions 1. Avoid repeated courses and prolonged treatment
2. Reduce doses in hepatic impairment
3. Renal impairment
4. Blood counts required before and periodically during treatment
5. Monitor plasma chloramphenicol concentration in neonates
6. Interactions
Adverse Effects1. Blood disorders
2. Peripheral neuritis
3. Optic neuritis
4. headache
5. Depression
6. Erythema multiforme
7. Nocturnal haemoglobinuria
8. May follow excessive doses in
neonates with immature hepatic metabolism
Pregnancy Category C

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