Amikacin- Indications, Dosage, and popular Brands

Category of DrugAnti-Infectives
Read more: Which are the popular antibiotics prescribed for infections? 
Mechanism of ActionAs an aminoglycoside, Amikacin binds to bacterial 30S ribosomal subunits and interferes with mRNA binding and tRNA acceptor sites, interfering with bacterial growth. 
IndicationsAmikacin is used in the short-term treatment of bacterial infections due to Gram-negative
bacteria, including Pseudomonas species, Escherichia coli, Klebsiella, Enterobacter, Serratia species
Well Known
Pharmaceutical Brands

1.       Omnikacin-Cipla
2.       Mikastar- Mankind
3.       Mikacin- Aristo
4.       Mik- Galpha Labs
5.       Macmika- Macleods
6.       La-Mika- Emcure
7.       Amitax- Alkem
8.       Amikamac- Macleods
9.       Amiject- Alkem
10.   Amicin- Zydus Cadila
11.   Alinfec- Abbott
12.   Alfakim- Sun
Available dosage formsINJECTION
Amikacin Sulphate Injection, for Hospital, Packaging Type: Vial, Rs 15 /box  | ID: 14719881730
DoseAdult- 15 mg/kg body weight daily in two divided doses (max 1.5g daily for 10 days, max. cumulative dose is 15g).
ContraindicationsMyasthenia gravis
renal impairment
neonates, infants, and elderly;
cross allergenicity
Adverse Effectsnephrotoxicity
nausea, vomiting, rash
Pregnancy CategoryD


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