| Parameters | Details |
|---|---|
| Category of Drug | Antiallergics and Drugs used in Anaphylaxis |
| Mechanism of Action | Adrenaline is a direct-acting sympathomimetic agent. Adrenaline may be used to provide rapid relief of severe hypersensitivity reaction to drugs and other allergens and in the emergency treatment of anaphylactic shock. |
| Chemical structure |  |
| IUPAC Name | 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol hydrochloride |
| Molecular details | Weight: 219.665 Chemical Formula-C9H14ClNO3 |
| Indications | Adrenaline Drug is used in 1. Severe anaphylactic reaction 2. Severe angioedema 3. Cardiac arrest 4. hemostatic agent |
| Well Known Pharmaceutical Brands | 1. ADRENOR- SAMARTH PHARMA 2. NORAD- NEON LABS 3. VASOCON- NEON LABS 4. NORADRIA- TROIKAA PHARMA 5. NORBIT- CELON LAB |
| Available dosage forms | INJECTION |
| Dose | 0.3 to 0.5 mg of undiluted Adrenalin administered intramuscularly or subcutaneously, up to a maximum of 0.5 mg (0.5 mL) per injection, repeated every 5 to 10 minutes as necessary. |
| Contraindications | 1. Narrow angle glaucoma 2. Organic brain damage 3. Cardiac dilation 4. Coronary insufficiency. |
| Precautions | 1. Hyperthyroidism 2. Hypertension 3. Diabetes Mellitus 4. Heart disease 5. Arrhythmias 6. Cerebrovascular disease 7. Second stage of labor 8. Elderly 9. Interactions 10. pregnancy 11. lactation |
| Adverse Effects | 1. Epinephrine fastness 2. Tachycardia and arrhythmias 3. Hypertension 4. Tremor 5. Anxiety 6. Sweating 7.Nausea 8. Vomiting 9. Weakness 10. Hyperglycaemia 11. Dizziness 12. Pulmonary 13.headache |
| Pregnancy Category | C |
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