Category of Drug | Chloramphenicol-Ophthalmological is Ophthalmological Preparations drug |
Mechanism of Action | |
Indications | Chloramphenicol-Ophthalmological is used for 1. Susceptible bacterial infections 2. Corneal ulcers 3. Intraocular infection 4. Keratoconjunctivitis sicca |
Well Known Pharmaceutical Brands | |
Available dosage forms | 1. OINTMENT 2. DROPS 3. SUSPENSION |
Dose | |
Contraindications | 1. Pregnancy 2. Lactation 3. Porphyria 4. Hypersensitivity |
Precautions | 1. Avoid repeated courses and prolonged treatment 2. Reduce doses in hepatic impairment 3. Renal impairment 4. Blood counts required before and periodically during treatment 5. Monitor plasma chloramphenicol concentration in neonates 6. Interactions |
Adverse Effects | 1. Blood disorders 2. Peripheral neuritis 3. Optic neuritis 4. headache 5. Depression 6. Erythema multiforme 7. Nocturnal haemoglobinuria 8. May follow excessive doses in neonates with immature hepatic metabolism |
Pregnancy Category | C |