| Category of Drug | Diazepam is an Anticonvulsants/Antiepileptics |
| Mechanism of Action | |
| Indications | Diazepam is used for 1. Status epilepticus 2. Emergency management of recurrent seizures 3. Febrile convulsions 4. Seizures associated with poisoning and medicine withdrawal 5. Adjunct in acute alcohol withdrawal 6. Premedication 7. Anxiety disorders 8. Psychosomatic behaviour disorder 9. Spasticity. |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | 1. TABLETS 2. CAPSULE 3. SUSPENSION 4. INJECTION |
| Dose | |
| Contraindications | 1. Respiratory depression 2. Acute pulmonary 3. Insufficiency 4. Sleep apnoea 5. Severe hepatic impairment 6. Myasthenia Gravis 7. Avoid injections containing benzyl alcohol in neonates 8. Narrow-angle glaucoma 9. Hypersensitivity to benzodiazepine. |
| Precautions | 1. Respiratory disease 2. Muscle weakness 3. History of alcohol or drug abuse 4. Marked personality disorder 5. Pregnancy 6. lactation 9. Reduce dose in elderly or debilitated patients and in hepatic impairment 10. Renal impairment 11. Avoid prolonged use and abrupt withdrawal 12. when given intravenously 13. Facilities for reversing respiratory depression |
| Adverse Effects | 1. Drowsiness and lightheadedness the next day 2. Confusion and ataxia 3. Amnesia 4. Dependence 5. Paradoxical increase in aggression 6. Muscle weakness 7. Occasionally headache 8. vertigo 9. salivation changes 10. Gastrointestinal disturbances 11. Visual disturbances 12. Dysarthria 13. urinary retention 14. blood disorders and jaundice |
| Pregnancy Category | D |
