Trihexyphenidyl (Benzhexol)

Trihexyphenidyl (Benzhexol)-Drug Detail Profile

Category of DrugTrihexyphenidyl (Benzhexol) is an Anti-Alzheimer and Anti-Parkinsonism Drugs.
Mechanism of Action 
Indications Trihexyphenidyl (Benzhexol) is used for
1. All forms of parkinsonism other than
2. Control of extrapyramidal disorders caused by CNS drugs.
Well Known
Pharmaceutical Brands
Available dosage forms1. TABLETS
Contraindications1. Avoided in gastrointestinal obstruction and
myasthenia gravis
2. Closed-angle glaucoma
3. Chronic pulmonary disease
4. Sick sinus syndrome
5. Thyrotoxicosis
6. Tachycardia
Precautions 1. Use with caution in cardiovascular disease,
2. Psychotic disorders,prostatic hypertrophy, pyrexia, in those susceptible to angle-closure glaucoma and in the elderly
3. It should not be withdrawn abruptly in patients receiving long-term treatment.
4. Anmuscarinics are liable to abuse.
5. Elderly males with possible prostate
6. Tardive dyskinesia
7. Neuroleptic malignant syndrome
Adverse Effects1. Constipation
2. Dry mouth
3. Nausea
4. Vomiting
5. Tachycardia
6. Dizziness
7. Confusion
8. Euphoria
9. Hallucinations
10. Impaired memory
11. Anxiety
12. Angle-closure glaucoma may occur
very rarely
13. Paralytic ileus
14. Dilation of the colon.
Pregnancy Category C

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