Sulphadiazine- Drug Detail Profile

Category of DrugSulphadiazine is an Anti-Infective drug 
Mechanism of Action 
Indications Sulphadiazine is used for
1. Prevention of recurrences of rheumatic
2. Toxoplasmosis
3. Prophylaxis of meningococcal infections.
Well Known
Pharmaceutical Brands
Available dosage forms TABLET
Contraindications1. Hypersensitivity to sulfonamides
2. porphyria
3. Severe renal hepatic impairment
4. Blood dyscrasias
5. Elderly
Precautions 1. Hepatic impairment
2. Renal impairment
3. Maintain adequate fluid intake
4. avoid in blood disorders
5. Monitor blood counts and discontinue immediately if blood disorder develops
6. rashes discontinue immediately
Adverse Effects 1. Nausea
2. Vomiting
3. Diarrhoea
4. Headache
5. Hypersensitivity reactions
6. Toxic epidermal necrolysis
7. Systemic lupus erythematosus
8. Myocarditis
9. Serum sickness
10. Crystalluria-resulting in haematuria
11. Oliguria/anuria
12. Blood Disorders
Pregnancy Category C

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