Proguanil

Primaquine- Drug Detail Profile

Category of DrugPrimaquine is an Anti-Infective drug
Mechanism of Action 
Indications Primaquine is used for
1. Radical cure of P. vivax and P. ovalemalaria
2. elimination of gametocytes of P. Falciparum, malaria prophylaxis.
Well Known
Pharmaceutical Brands
 
Available dosage forms TABLETS
Dose
Contraindications1. Hypersensitivity
2. Granulocytopenia
3. Pregnancy
4. Lactation
5. Children below 1 year
Precautions  1. Patients with a history of granulocytosis/
methaemoglobinaemia
2. G-6-PD deficiency
3. Monitor Hb levels
4. Blood counts routinely
and withdraws if signs of haemolysis or
methaemoglobinaemia occur
5. lactation
Adverse Effects 1. Nausea
2. Vomiting
3. Abdominal cramps
4. Haemolytic anaemia in G-6-PD deficient
patients
5. Leukopenia
6. Agranulocytosis
7. leukocytosis
8. Methaemoglobinaemia and cardiac arrhythmias.
Pregnancy Category 

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