Category of Drug | Phenobarbitone is a Anticonvulsants/Antiepileptics drug |
Mechanism of Action | |
Indications | Phenobarbitone is used for 1. Generalized tonic-clonic seizures 2. Partial seizures 3. Neonatal seizures 4. Febrile convulsions 5. Status epilepsy 6. Sedative 7. Hypnotic 8. Pre-anaesthetic. |
Well Known Pharmaceutical Brands | |
Available dosage forms | 1. TABLETS 2. INJECTION 3. SYRUP |
Dose | |
Contraindications | 1. Absence seizures 2. Latent porphyria. |
Precautions | 1. Elderly 2. Debilitated 3. Children 4. Impaired Renal function 5. Respiratory Depression 6. Pregnancy 7. Lactation 8. Avoid sudden withdrawal |
Adverse Effects | 1. Sedation, mental depression, agitation, hallucination, syncope; 2. Ataxia, nystagmus; 3. Allergic skin reactions including rarely, exfoliative dermatitis, toxic epidermal necrolysis, Steven’s- Johnson syndrome 4. Paradoxical excitement 5. Restlessness and confusion in the elderly 6. Irritability and hyperactivity in children |
Pregnancy Category | D |