| Parameters | Description |
|---|---|
| Category of Drug | Methyldopa is Antihypertensive Drugs |
| Mechanism of Action | |
| Indications | Methyldopa is used for Hypertension in pregnancy |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | TABLET |
| Dose | |
| Contraindications | 1. Depression 2. active liver disease 3. Hypersensitivity 4. Therapy with MAO inhibitors 5. Pheochromocytoma 6. Porphyria |
| Precautions | 1. History of hepatic impairment 2. Renal impairment 3. Blood counts and liver function tests advised 4. History of depression 5. Positive direct Coomb test in up to 20% of patients 6. Interference with laboratory tests 7. lactation 8. Pregnancy |
| Adverse Effects | 1. Tend to be transient and reversible including sedation 2. Dizziness 3. Lightheadedness 4. Postural hypotension 5. Weakness 6. Fatigue 7. Headache 8. Fluid retention and oedema 9. Sexual dysfunction 10. Impaired concentration and memory 11. Arthralgia 12. Paraesthesia 13. Bell palsy 14. Pancreatitis |
| Pregnancy Category | B |
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