Methyldopa- Indications, Dosage, Contraindications, ADRs

Category of Drug Methyldopa is Antihypertensive Drugs
Mechanism of Action 
Indications Methyldopa is used for
Hypertension in pregnancy
Well Known
Pharmaceutical Brands
Available dosage forms TABLET
Contraindications1. Depression
2. active liver disease
3. Hypersensitivity
4. Therapy with MAO inhibitors
5. Pheochromocytoma
6. Porphyria
Precautions 1. History of hepatic impairment
2. Renal impairment
3. Blood counts and liver function tests advised
4. History of depression
5. Positive direct Coomb test in up to 20% of patients
6. Interference with laboratory tests
7. lactation
8. Pregnancy
Adverse Effects 1. Tend to be transient and reversible including sedation
2. Dizziness
3. Lightheadedness
4. Postural hypotension
5. Weakness
6. Fatigue
7. Headache
8. Fluid retention and oedema
9. Sexual dysfunction
10. Impaired concentration
and memory
11. Arthralgia
12. Paraesthesia
13. Bell palsy
14. Pancreatitis
Pregnancy Category B

1 thought on “Methyldopa- Indications, Dosage, Contraindications, ADRs”

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