Isotretinoin- Indications, Dosage, Contraindications, ADRs

Category of DrugIsotretinoin- Dermatological Drugs- Drugs Affecting Skin Differentiation and Proliferation
Mechanism of Action 
IndicationsIsotretinoin- Dermatological Drugs- Drugs Affecting Skin Differentiation and Proliferation which is used for
1. Resistant and severe nodulocystic acne
2. Dry scaly surface
3. Moling
4. Wrinkles
5. Rough and leathery texture
6. Acute promyelocytic
7. actinic keratoses
Well Known
Pharmaceutical Brands
Available dosage forms1. TABLET
4. GEL
Contraindications1. Female patients who are or may become pregnant
2. Lactation
3. Hypersensitivity
4. Acute eczematous
5. Sunburnt or abraded skin
6. Hypervitaminosis of Vitamin A
7. Hyperlipidemia
8. Pancreas
Precautions1. Contraceptive measures must be followed for any subsequent course of therapy
2. Concomitant application with keratolytic agents
3. Avoid exposure to sunlight and UV light
4. Renal and hepatic impairment
5. Interactions
Adverse Effects1. Dryness of skin and mucous membranes
2. Pruritus
3. Epistaxis
4. Cheilitis
5. Erythema
6. Sometimes Stevens-Johnson syndrome
7. Paresthesias
8. Anxiety
9. Conjunctivitis
10. Paronychia
Pregnancy Category X

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