Category of Drug | Isotretinoin- Dermatological Drugs- Drugs Affecting Skin Differentiation and Proliferation |
Mechanism of Action | |
Indications | Isotretinoin- Dermatological Drugs- Drugs Affecting Skin Differentiation and Proliferation which is used for 1. Resistant and severe nodulocystic acne 2. Dry scaly surface 3. Moling 4. Wrinkles 5. Rough and leathery texture 6. Acute promyelocytic leukaemia 7. actinic keratoses |
Well Known Pharmaceutical Brands | |
Available dosage forms | 1. TABLET 2. CAPSULES 3. CREAM 4. GEL 5. OINTMENT |
Dose | |
Contraindications | 1. Female patients who are or may become pregnant 2. Lactation 3. Hypersensitivity 4. Acute eczematous 5. Sunburnt or abraded skin 6. Hypervitaminosis of Vitamin A 7. Hyperlipidemia 8. Pancreas |
Precautions | 1. Contraceptive measures must be followed for any subsequent course of therapy 2. Concomitant application with keratolytic agents 3. Avoid exposure to sunlight and UV light 4. Renal and hepatic impairment 5. Interactions |
Adverse Effects | 1. Dryness of skin and mucous membranes 2. Pruritus 3. Epistaxis 4. Cheilitis 5. Erythema 6. Sometimes Stevens-Johnson syndrome 7. Paresthesias 8. Anxiety 9. Conjunctivitis 10. Paronychia |
Pregnancy Category | X |