| Category of Drug | Imipenem + Cilastatin is an Anti-Infective drug |
| Mechanism of Action | |
| Indications | Imipenem + Cilastatin is used for Severe aerobic and anaerobic Gram-positive and Gram-negative infections in hospital-acquired infections |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | INJECTION |
| Dose | |
| Contraindications | 1. Hypersensitivity to beta-lactam antibiotics 2. Local anaesthetics of the amide-type and in patients with severe shock or heart block. |
| Precautions | 1. Renal impairment 2. CNS disorders 3. Pregnancy 4. Lactations 5. Interactions |
| Adverse Effects | 1. Nausea 2. Vomiting 3. Diarrhoea 4. Antibiotic-associated colitis 5. Taste disturbances 6. Tooth or tongue discolouration 7. Hearing loss 8. Blood disorders 9. Positive Coombs’ test 10. Allergic reactions 11. A slight increase in liver enzymes and bilirubin |
| Pregnancy Category | C |
