| Category of Drug | Hydralazine is Antihypertensive Drugs |
| Mechanism of Action | |
| Indications | Hydralazine is used for 1. In combination therapy in moderate to severe hypertension 2. Hypertensive crisis 3. Hypertension associated with pregnancy |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | 1. TABLET 2. INJECTION |
| Dose | |
| Contraindications | 1. Idiopathic systemic lupus erythematosus 2. Severe tachycardia 3. High output heart failure 4. Myocardial insufficiency due to mechanical obstruction 5. Cor pulmonale 6. Dissecting aortic aneurysm 7. Porphyria 8. Angina 9. Mitral valvular heart disease 10. Rheumatic disease |
| Precautions | 1. Hepatic impairment 2. Renal impairment 3. Coronary artery disease 4. Cerebrovascular disease 5. Check acetylator status before increasing dose above 100 mg daily 6. Test for antinuclear factor and for proteinuria every 6 months 7. Coronary artery disease 8. Alcohol intake 9. Lactation |
| Adverse Effects | 1. Tachycardia 2. Palpitations 3. Postural hypotension 4. Fluid retention 5. Gastrointestinal disturbances 6. Constipation 7. Dizziness 8. Flushing 9. Headache 10. Abnormal liver function 11. Systemic lupus erythematosus-like syndrome |
| Pregnancy Category | C |
