Fluphenazine- Indications, Dosage, Contraindications, ADRs

Category of Drug Fluphenazine is Antipsychotics drug
Mechanism of Action 
Indications Fluphenazine is used for
1. Maintenance treatment of schizophrenia and other psychoses
2. Mania
3. Postoperative nausea
Well Known
Pharmaceutical Brands
Available dosage forms1. TABLET
Contraindications1. Children
2. Confusional states
3. Impaired consciousness due to CNS depression
4. Parkinsonism
5. Intolerance to antipsychotics
6. Depression
7. Bone-marrow depression
8. Pheochromocytoma
9. Blood dyscrasias
10. Coma
11. Brain damage
Precautions1. Treatment requires careful monitoring for optimum effect
2. Initial small test dose as adverse effects are prolonged
3. Extrapyramidal symptoms occur frequently
4. When transferring from oral to depot therapy
5. Dosage by mouth should be reduced gradually
6. Cardiovascular and cerebrovascular
7. Respiratory disease
8. Epilepsy
9. Acute infections
9. Pregnancy
Adverse Effects1. Sedantig and fewer hypotensive and anticholinergic symptoms
2. Higher incidence
of extrapyramidal symptoms
3. Systemic lupus erythematosus
4. Pain at the injection site
5. Neurological disturbances
Pregnancy Category C

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